PUBLICATIONS

Books, Journal Articles, & Conferences

  • Kim, J. J. H., Um, R., Iyer, R., Theodore, N., & Manbachi, A. (2022).

    Design and Development of Smart Surgical Assistant Technologies (1st ed.).

    CRC Press.

    https://doi.org/10.1201/9781003253341

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    Manbachi, A., Kempski Leadingham, K. M., & Curry, E. J. (Eds.). (2022).

    The Abundant Promise of Ultrasound in Neurosurgery: A Broad Overview and Thoughts on Ethical Paths to Realizing its Benefits (1st ed.)

    SPIE Press.

    https://spie.org/Publications/Book/2653274?&origin_id=x653&SSO=1

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    Manbachi, A., & Suk, I. (2021)

    Handbook for Clinical Ultrasound: Beginner’s Guide to Fundamental Physics & Medical Ultrasound Applications.

    Independently published.

    https://www.amazon.com/Handbook-Clinical-Ultrasound-Fundamental-Applications/dp/B096TRVW4F

  • ORIGINAL RESEARCH

    Abramson, H. G., Curry, E. J., Mess, G., Thombre, R., Kempski-Leadingham, K. M., Mistry, S., Somanathan, S., Roy, L., Abu-Bonsrah, N., Coles, G., Doloff, J. C., Brem, H., Theodore, N., Huang, J., & Manbachi, A. (2022).

    Automatic Detection of Foreign Body Objects in Neurosurgery Using a Deep Learning Approach on Intraoperative Ultrasound Images: From Animal Models to First In-Human Testing.

    Frontiers in Surgery, 9.

    https://doi.org/10.3389/fsurg.2022.1040066

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    Aghabaglou, F., Ainechi, A., Abramson, H., Curry, E., Kaovasia, T. P., Kamal, S., Acord, M., Mahapatra, S., Pustavoitau, A., Smith, B., Azadi, J., Son, J. K., Suk, I., Theodore, N., Tyler, B. M., & Manbachi, A. (2022).

    Ultrasound Monitoring of Microcirculation: An Original Study from the Laboratory Bench to the Clinic.

    Microcirculation, 29(6–7).

    https://doi.org/10.1111/micc.12770

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    Bhimreddy, M., Routkevitch, D., Hersh, A. M., Mohammadabadi, A., Menta, A. K., Jiang, K., Weber-Levine, C., Davidar, A. D., Punnoose, J., Kempski Leadingham, K. M., Doloff, J. C., Tyler, B., Theodore, N., & Manbachi, T. (2023).

    Disruption of the Blood-Spinal Cord Barrier using Low-Intensity Focused Ultrasound in a Rat Model.

    Journal of Visualized Experiments, Vol 193.

    https://doi.org/10.3791/65113

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    Liang, R., Mess, G., Punnoose, J., Kempski Leadingham, K. M., Smit, C., Thakor, N., Habela, C. W., Tyler, B., Salimpour, Y., & Manbachi, A. (Submitted 2022).

    Focused Ultrasound Neuromodulation of Human in vitro Neural Culture in Multi-well Microelectrode Array.

    Journal of Visualized Experiments.

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    Mess, G., Anderson, T., Kapoor, S., Thombre, R., Liang, R., Derin, E., Kempski-Leadingham, K. M., Yadav, S. K., Tyler, B., & Manbachi, A. (2023).

    Sonodynamic Therapy for the Treatment of Glioblastoma Multiforme in a Mouse Model Using a Portable Benchtop Focused Ultrasound System.

    Journal of Visualized Experiments, 192.

    https://doi.org/10.3791/65114

    •.• • • •

    Tsehay, Y., Zeng, Y., Weber-Levine, C., Awosika, T., Kerensky, M., Hersh, A. M., Ou, Z., Jiang, K., Bhimreddy, M., Bauer, S. J., Theodore, J. N., Quiroz, V. M., Suk, I., Alomari, S., Sun, J., Tong, S., Thakor, N., Doloff, J. C., Theodore, N., & Manbachi, A. (2023).

    Low-Intensity Pulsed Ultrasound Neuromodulation of a Rodent’s Spinal Cord Suppresses Motor Evoked Potentials.

    IEEE Transactions on Biomedical Engineering, 1–11.

    https://doi.org/10.1109/TBME.2022.3233345

    REVIEW PAPERS

    Hersh, A. M., Bhimreddy, M., Weber-Levine, C., Jiang, K., Alomari, S., Theodore, N., Manbachi, A., & Tyler, B. M. (2022).

    Applications of Focused Ultrasound for the Treatment of Glioblastoma: A New Frontier.

    Cancers, 14(19), 4920.

    https://doi.org/10.3390/cancers14194920

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    Hersh, A. M., Weber-Levine, C., Jiang, K., Young, L., Kerensky, M., Routkevitch, D., Tsehay, Y., Perdomo-Pantoja, A., Judy, B. F., Lubelski, D., Theodore, N., & Manbachi, A. (2022).

    Applications of Elastography in Operative Neurosurgery: A Systematic Review.

    Journal of Clinical Neuroscience, 104, 18–28.

    https://doi.org/10.1016/j.jocn.2022.07.019

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    Hwang, B. Y., Mampre, D., Ahmed, A. K., Suk, I., Anderson, W. S., Manbachi, A., & Theodore, N. (2022).

    In Reply: Ultrasound in Traumatic Spinal Cord Injury: A Wide-Open Field.

    Neurosurgery, 90(3), e80–e80.

    https://doi.org/10.1227/NEU.0000000000001812

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    Hwang, B. Y., Mampre, D., Ahmed, K. A., Suk, I., Anderson, W. S., Manbachi, A., & Theodore, N. (2021).

    Ultrasound in Traumatic Spinal Cord Injury: A Wide-Open Field.

    Neurosurgery, 89(3), 372–382.

    https://doi.org/10.1093/neuros/nyab177

    •.• • • •

    Sadeghi, A. H., Koldeweij, C., Trujillo-de Santiago, G., Tannazi, M., Hosseinnia, N., Loosbroek, O. van, Manbachi, A., Taverne, Y. J. H. J., Bogers, A. J. J. C., & Alvarez, M. M. (2021).

    Social Non-profit Bioentrepreneurship: Current Status and Future Impact on Global Health.

    Frontiers in Public Health, 9.

    https://doi.org/10.3389/fpubh.2021.541191

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    Thombre, R., Mess, G., Kempski Leadingham, K. M., Kapoor, S., Hersh, A., Acord, M., Kaovasia, T., Theodore, N., Tyler, B., & Manbachi, A. (2023).

    Towards Standardization of the Parameters for Opening the Blood–Brain Barrier with Focused Ultrasound to Treat Glioblastoma Multiforme: A Systematic Review of the Devices, Animal Models, and Therapeutic Compounds used in Rodent Tumor Models.

    Frontiers in Oncology, 12.

    https://doi.org/10.3389/fonc.2022.1072780

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    Tsehay, Y., Weber-Levine, C., Kim, T., Chara, A., Alomari, S., Awosika, T., Liu, A., Ehresman, J., Lehner, K., Hwang, B., Hersh, A. M., Suk, I., Curry, E., Aghabaglou, F., Zeng, Y., Manbachi, A., & Theodore, N. (2022).

    Advances in Monitoring for Acute Spinal Cord Injury: a Narrative Review of Current Literature.

    The Spine Journal, 22(8), 1372–1387.

    https://doi.org/10.1016/j.spinee.2022.03.012

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    Weber-Levine, C., Hersh, A. M., Jiang, K., Routkevitch, D., Tsehay, Y., Perdomo-Pantoja, A., Judy, B. F., Kerensky, M., Liu, A., Adams, M., Izzi, J., Doloff, J. C., Manbachi, A., & Theodore, N. (2022).

    Porcine Model of Spinal Cord Injury: A Systematic Review.

    Neurotrauma Reports, 3(1), 352–368.

    https://doi.org/10.1089/neur.2022.0038

  • Abramson, H., Curry, E., Sampath, K., Wissman, J., Mess, G., Thombre, R., Mahapatra, S., Aghabaglou, F., Theodore, N., Pustavoitau, A., & Manbachi, A. (2022, April 11).

    Towards A Universal Device for Point-of-Care Medicine: A Custom Transducer for Long-Term Monitoring of Local Vascular Flow Via Ultrasound Imaging.

    2022 Design of Medical Devices Conference.

    https://doi.org/10.1115/DMD2022-1006

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    Acord, M., Kaovasia, T. P., Gamo, N. J., Xiong, T., Curry, E., Aghabaglou, F., Morrison, K., Tyler, B., Luciano, M., & Manbachi, A. (2021, April 12).

    Design and Fabrication of a Focused Ultrasound Device for Minimally Invasive Neurosurgery: Reporting a Second, Miniaturized and MR-Compatible Prototype with Steering Capabilities.

    2021 Design of Medical Devices Conference.

    https://doi.org/10.1115/DMD2021-1062

    •.• • • •

    Kerensky, M., Doloff, J. C., Thakor, N., Theodore, N., & Manbachi, A. (2022a). 216

    An Example for Establishing a Clinically Translational Innovation Lab at a University Setting.

    Journal of Clinical and Translational Science 35–35.

    https://doi.org/10.1017/cts.2022.118

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    Kerensky, M., Doloff, J. C., Thakor, N., Theodore, N., & Manbachi, A. (2022b). 524

    How Can I Provide My Patient Insights in a Nontraditional Advocacy Role?

    Journal of Clinical and Translational Science, 109–109.

    https://doi.org/10.1017/cts.2022.318

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    Kerensky, M., Liang, R., Curry, E., Thakor, N., Theodore, N., & Manbachi, A. (2022). 513

    Towards Obtaining One Billion Recordings Per Cubic Millimeter for the Validation of Focused Ultrasound Transducers: How Can Robust Systems Help With Translational Activities?

    Journal of Clinical and Translational Science, 6(s1), 105–105.

    https://doi.org/10.1017/cts.2022.307

    •.• • • •

    Kim, J. H., Um, R., Liu, J., Patel, J., Curry, E., Mahapatra, S., Ainechi, A., Tsehay, Y., Ehresman, J., Hwang, B., Tyler, B., Aghabaglou, F., Iyer, R., Theodore, N., & Manbachi, A. (2021).

    The Development of Smart Hospital Assistant: Integrating Artificial Intelligence and a Voice-User Interface for Improved Surgical Outcomes. In B. J. Park & T. M. Deserno (Eds.),

    Medical Imaging 2021: Imaging Informatics for Healthcare, Research, and Applications (p. 30). SPIE.

    https://doi.org/10.1117/12.2580995

    •.• • • •

    Kumar, A., Punnoose, J., Kempski Leadingham, K. M., Kerensky, M. J., Theodore, N., Thakor, N. v, & Manbachi, A. (2023, April 25).

    A Patient-specific Preplanning Treatment Algorithm for Focused Ultrasound Therapy of Spinal Cord Injury.

    IEEE/EMBS Conference on Neural Engineering.

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    Kumar, A., Tsehay, Y., Gonzalez, E., Kerensky, M. J., Bell, M. A. L., Theodore, N., Thakor, N. v, & Manbachi, A. (2023, February 20).

    Computational Modeling Towards Focused Ultrasound Therapy for Spinal Cord Injury: Visualization of Beam Propagation through Patient-Specific Anatomy.

    SPIE Medical Imaging.

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    Leadingham, K. M. K., Abramson, H. G., Perdomo-Pantoja, A., Thombre, R., Liu, J., Norman, M., Chavez, F., Morrison, K., Suk, I., Gordon, C., Armand, M., & Manbachi, A. (2022).

    Design of a Custom Flexible Ultrasound Transducer as an Implantable Cranial Sensor for Long-Term Post-Operative Monitoring of Brain Tumor Regrowth.

    2022 IEEE International Ultrasonics Symposium (IUS), 1–4.

    https://doi.org/10.1109/IUS54386.2022.9958345

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    Liang, R., Kerensky, M., Curry, E., Mess, G., Thombre, R., Kamal, S., Aghabaglou, F., Mejia, R., Chavez, F., Morrison, K., Thakor, N., Theodore, N., & Manbachi, A. (2022, April 11)

    Designing an Accurate Benchtop Characterization Device: An Acoustic Measurement Platform for Localizing and Implementing Therapeutic Ultrasound Devices and Equipment (Amplitude).

    2022 Design of Medical Devices Conference.

    https://doi.org/10.1115/DMD2022-1046

    •.• • • •

    Mahapatra, S., Balamurugan, M., Chung, K., Kuppoor, V., Curry, E., Aghabaglou, F., Kaovasia, T. P., Acord, M., Ainechi, A., Kim, J., Tsehay, Y., Ghinda, C. D., Son, J. K., Pustavoitau, A., Tyler, B., Theodore, N., Brem, H., Huang, J., & Manbachi, A. (2021)

    Automatic Detection of Cotton Balls During Brain Surgery: Where Deep Learning Meets Ultrasound Imaging to Tackle Foreign Objects.

    SPIE Medical Imaging 2021: Ultrasonic Imaging and Tomography, 116021C

    https://doi.org/10.1117/12.2580887

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    Mahapatra, S., Kaovasia, T. P., Ainechi, S., Ainechi, A., Acord, M., Curry, E. J., Aghabaglou, F., Tyler, B., Theodore, N., & Manbachi, A. (2021, April 12).

    Design of an Ultrasound Probe Holder to Minimize Motion Artifact During Sonography.

    2021 Design of Medical Devices Conference.

    https://doi.org/10.1115/DMD2021-1049

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    Manbachi, A., & Theodore, N. (2021). 90449

    Can Ultrasound Detect Changes to Spinal Cord Blood Flow Before and After Injury?

    Journal of Clinical and Translational Science, 6–6.

    https://doi.org/10.1017/cts.2021.418

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    Mess, G., Thombre, R., Kerensky, M., Curry, E., Aghabaglou, F., Alomari, S., Brem, H., Theodore, N., Tyler, B., & Manbachi, A. (2022, April 11).

    Designing a Murine Model of Human Glioblastoma Brain Tumor: Development of a Platform for Validation Using Ultrasound Elastography

    2022 Design of Medical Devices Conference.

    https://doi.org/10.1115/DMD2022-1025

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    Routkevitch, D., Hersh, A. M., Kempski, K. M., Kerensky, M., Theodore, N., Thakor, N. v., & Manbachi, A. (2022).

    FlowMorph: Morphological Segmentation of Ultrasound-Monitored Spinal Cord Microcirculation.

    2022 IEEE Biomedical Circuits and Systems (BioCAS) Conference, 610-614

    https://doi.org/10.1109/BioCAS54905.2022.9948639

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    Routkevitch, D., Menta, A. K., Kats, N., Baca, E., Soule, Z., Kempski Leadingham, K. M., Hersh, A. M., Theodore, N., Thakor, N. v, & Manbachi Amir. (2023, April 25).

    Measurement of Single-Vessel Flow Parameters for Vascular Characterization of Spinal Cord Injury.

    IEEE/EMBS Conference on Neural Engineering.

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    Thombre, R., Mess, G., Curry, E., Mejia, R., Liang, R., Aghabaglou, F., Kerensky, M., Abramson, H., VanSickle, R., Tyler, B., Theodore, N., & Manbachi, A. (2022, April 11)

    Design and Development of System Components for Therapeutic Ultrasound Devices: Enhancing Focused Ultrasound Treatments Using Cones with Clinical and Ergonomic Considerations.

    2022 Design of Medical Devices Conference.

    https://doi.org/10.1115/DMD2022-1030

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    Yoo, S. J., Mou, J., Elizebath, R., Sivakumar, A., DeBrabander, R., Shifman, M., Tu, K., Ishida, W., Fouda, M., Manbachi, A., & Cohen, A. R. (2021, April 12).

    The Design and Use of a Minimally-Invasive, Expandable Retractor for Deep-Seated Brain Lesions.

    2021 Design of Medical Devices Conference.

    https://doi.org/10.1115/DMD2021-1023

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    Zeng, Y., Acord, M., Kaovasia, T. P., Miao, P., Sun, J., Tong, S., Curry, E., Aghabaglou, F., Theodore, N., Thakor, N., & Manbachi, A. (2021, April 12).

    A Miniature Laser Speckle Contrast Imager for Monitoring the Neuromodulatory Effect of Transcranial Ultrasound Stimulation

    2021 Design of Medical Devices Conference.

    https://doi.org/10.1115/DMD2021-1038